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If the patient anticipates disconnecting the pump for a short period of time (< 2 hours such as to swim, shower, or short medical procedure), no supplemental oral medication is needed, but the patient may be advised to take an extra-dose of Duopa before disconnecting. The risk or severity of adverse effects can be increased when Suprofen is combined with Prednisone. Vigabatrin: (Minor) Vigabatrin is not significantly metabolized; however, it is an inducer of CYP2C9. This includes vitamins, herbal supplements and over the counter remedies. For years, consumers and doctors have relied on the power and speed of Mylanta Maximum Strength Liquid to help soothe and relieve heartburn, acid indigestion and bothersome gas symptoms to feel better fast. The serum concentration of Imipramine can be increased when it is combined with Simeprevir.