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The metabolism of Verapamil can be decreased when combined with Ixazomib. Postmortem forensic toxicology of selective serotonin reuptake inhibitors: a review of pharmacology and report of 168 cases". Relationship with serum concentrations of the drug. The metabolism of Estradiol can be decreased when combined with Efavirenz. The metabolism of Podofilox can be decreased when combined with Fluoxetine. However, acute urinary retention and kidney damage can be serious health threats.