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If you take the tablets out of the box or the blister pack they may not keep well. Discontinue if new or worsening symptoms occur. The serum concentration of Afatinib can be decreased when it is combined with Clotrimazole. In addition, antypsychotics may increase the risk of cerebrovascular accidents and also contribute to cortical atrophy after years of chronic treatment ( Cacabelos et al 1996 , 1997 ; Gill et al 2005). Comparison of a standard versus accelerated dosing regimen for D,L-sotalol for the treatment of atrial and ventricular dysrhythmias. Produce-filled diets can also help lower the risk of most cancers, according to the American Cancer Society, but research hasn't been done on aГ§aГ­ specifically.