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	Patients should be instructed to report hematuria, dysuria, or urinary urgency promptly. The metabolism of Venlafaxine can be decreased when combined with Topiramate. Gemifloxacin may increase the QTc-prolonging activities of Amiodarone. The metabolism of Rosuvastatin can be decreased when combined with Manidipine. Dapoxetine for the treatment of premature ejaculation: Lack of interaction with ethanol". It is generally not necessary to exceed 3 g of paracetamol per day, ie 3 tablets per day.

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