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Evidence for effectiveness for this disease, however, is poor. As of 2009, "hundreds more such suits have since been filed. Precursor drugs to repaglinide were invented in late 1983 by scientists at Dr Karl Thomae GmbH, a German drug manufacturer located at Biberach an der RiГџ in southern Germany which was acquired by Boehringer Ingelheim in 1990. It is not possible to determine whether these events were directly related to Caverta by Ranbaxy. One trial found that among those likely having an ST-segment elevation MI, aspirin saves the life of 1 in 42 by reducing the 30-day death rate from 11. LABA such as fluticasone and salmeterol combination (Advair) or formoterol (Foradil).