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A Magyar Rovartani Társaság 756. As mentioned earlier, there is no actual difference in the mechanism of action of both drugs. Adults—25 to 50 mg, injected into a muscle three or four times a day. Metoprolol may increase the bradycardic activities of Digitoxin. You should have regular eye exams while using SYMBICORT. Following ophthalmic administration, prednisolone is absorbed through the aqueous humor, with only minimal systemic absorption occurring.