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Figure 2 depicts the percent mean improvement in maximal walking distance, at study end for each of the eight studies. But that's the side affects of the meds. A 1-cm (approximately в…“ inch) strip of ointment is usually enough, unless you have been told by your doctor to use a different amount. Bucindolol may increase the orthostatic hypotensive activities of Tamsulosin. The Cochrane Database of Systematic Reviews (7): CD008190. Cholestyramine can cause a decrease in the absorption of Prednisolone resulting in a reduced serum concentration and potentially a decrease in efficacy.